Effect of nucleotide excision repair on ENU-induced mutation in female germ cells of Drosophila melanogaster.

doi:10.1002/em.10149

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Article

Effect of nucleotide excision repair on ENU-induced mutation in female germ cells of Drosophila melanogaster.

Environmental and molecular mutagenesis - 1 Jan 2003

Alvarez L, Comendador M A, Sierra L M

Abstract excerpt

The role of nucleotide excision repair (NER) in the repair of alkylation damage in the germ cells of higher eukaryotes has been studied mainly by treating postmeiotic male germ cells. Little is known about repair in actively repairing female germ cells. In this study, we treated NER-deficient (ner(-)) mus201(D1) Drosophila females with N-ethyl-N-nitrosourea (ENU) and determined both the mutant frequencies in the...

Topics

Animals
Base Sequence
DNA Primers
DNA Repair
Drosophila Proteins
Drosophila melanogaster
Ethylnitrosourea
Eye Proteins
Female
Germ Cells
Mutagens
Mutation
Tryptophan Oxygenase

Source

Open in PubMed

Identifiers

PMID: 12717782
DOI: 10.1002/em.10149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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