Article
Mechanisms for dominance: Adh heterodimer formation in heterozygotes between ENU or X-ray induced null alleles and normal alleles in Drosophila melanogaster.
Environmental and molecular mutagenesis - 1 Jan 1992
Jiang J C, Lee W R, Chang S H, Silverman H
Abstract excerpt
To study mechanisms for dominance of phenotype, eight ENU- and four X-ray-induced mutations at the alcohol dehydrogenase (Adh) locus were analyzed for partial dominance in their interaction with normal alleles. All ENU and one of the X-ray mutations were single base substitutions; the other three...
Topics
- Alcohol Dehydrogenase
- Alleles
- Animals
- Base Sequence
- Blotting, Western
- Crosses, Genetic
- Drosophila melanogaster
- Electrophoresis, Agar Gel
- Electrophoresis, Polyacrylamide Gel
- Ethylnitrosourea
- Gene Expression
- Gene Expression Regulation, Enzymologic
- Genes, Dominant
- Genes, Insect
- Heterozygote
- Molecular Sequence Data
- Phenotype
- Protein Biosynthesis