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Article

ENU mutagenesis in the mouse electrophoretic specific-locus test. 2. Mutational studies of mature oocytes.

Mutation research - 1 Dec 1992

Lewis S E, Barnett L B, Shelby M D

Abstract excerpt

Experiments were conducted using the biochemical specific-locus test to assess the mutagenicity of N-ethyl-N-nitrosourea (ENU) in mature oocytes of mice. C57Bl/6J females were treated with 100 mg/kg ENU by intraperitoneal injection and mated to untreated DBA males for 1 week following treatment. 1447 progeny were screened for evidence of mutations affecting the electrophoretic mobility of 32 different proteins;...

Topics

Animals
Crosses, Genetic
Electrophoresis
Ethylnitrosourea
Female
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mutagenesis
Mutagenicity Tests
Oocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1279399
DOI: 10.1016/0165-1110(92)90036-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1279399-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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