Article
ENU mutagenesis in the mouse electrophoretic specific-locus test. 2. Mutational studies of mature oocytes.
Mutation research - 1 Dec 1992
Lewis S E, Barnett L B, Shelby M D
Abstract excerpt
Experiments were conducted using the biochemical specific-locus test to assess the mutagenicity of N-ethyl-N-nitrosourea (ENU) in mature oocytes of mice. C57Bl/6J females were treated with 100 mg/kg ENU by intraperitoneal injection and mated to untreated DBA males for 1 week following treatment. 1447 progeny were screened for evidence of mutations affecting the electrophoretic mobility of 32 different proteins;...
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