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Article

Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens.

Developmental biology - 1 Feb 2011

Tittle Rachel K, Sze Ryan, Ng Anthony, Nuckels Richard J, Swartz Mary E, Anderson Ryan M, Bosch Justin, Stainier Didier Y R, Eberhart Johann K, Gross Jeffrey M

Abstract excerpt

DNA methylation is one of the key mechanisms underlying the epigenetic regulation of gene expression. During DNA replication, the methylation pattern of the parent strand is maintained on the replicated strand through the action of Dnmt1 (DNA Methyltransferase 1). In mammals, Dnmt1 is recruited to hemimethylated replication foci by Uhrf1 (Ubiquitin-like, Containing PHD and RING Finger Domains 1). Here we show...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21126517
DOI: 10.1016/j.ydbio.2010.11.009
PMCID: PMC3022120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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