Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina.

Experimental eye research - 1 Jun 2017

Singh Ratnesh K, Mallela Ramya K, Hayes Abigail, Dunham Nicholas R, Hedden Morgan E, Enke Raymond A, Fariss Robert N, Sternberg Hal, West Michael D, Nasonkin Igor O

Abstract excerpt

Characterizing the role of epigenetic regulation in the mammalian retina is critical for understanding fundamental mechanisms of retinal development and disease. DNA methylation, an epigenetic modifier of genomic DNA, plays an important role in modulating networks of tissue and cell-specific gene expression. However, the impact of DNA methylation on retinal development and homeostasis of retinal neurons remains...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA (Cytosine-5-)-Methyltransferase 1
Share to DNA (Cytosine-5-)-Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methyltransferase 3A

Share to DNA Methyltransferase 3B

Share to Immunoblotting

Share to Microscopy, Electron

Share to Models, Animal

Share to Photoreceptor Cells, Vertebrate

Source

Identifiers

PMID: 27865785
DOI: 10.1016/j.exer.2016.11.014

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina.PMID 27865785Read ↗

Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesisSemantic proximity Read ↗

DNA methylation and differential gene regulation in photoreceptor cell death.Semantic proximity Read ↗

DNA methylation plays important roles in retinal development and diseasesSemantic proximity Read ↗

DNA demethylation is a driver for chick retina regenerationSemantic proximity Read ↗

Transient DNA methyltransferase 3a (DNMT3a) Inhibition Unlocks dedifferentiation and Neurogenic Potential in Mouse Retinal Müller GliaSemantic proximity Read ↗

Dysregulated DNA Methylation in Retinal Pigment Epithelium During the Early Stage of Stargardt DiseaseSemantic proximity Read ↗

DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated DisordersSemantic proximity Read ↗

Epigenetic regulation of retinal development and diseaseSemantic proximity Read ↗

Advances in Ophthalmic Epigenetics and Implications for Epigenetic Therapies: A ReviewSemantic proximity Read ↗

Dynamic Patterns of Histone Lysine Methylation in the Developing RetinaSemantic proximity Read ↗

Suppressing DNMT3a Alleviates the Intrinsic Epigenetic Barrier for Optic Nerve Regeneration and Restores Vision in Adult MiceSemantic proximity Read ↗

Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.