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Article

Liver growth in the embryo and during liver regeneration in zebrafish requires the cell cycle regulator, uhrf1.

Proceedings of the National Academy of Sciences of the United States of America - 30 Jan 2007

Sadler Kirsten C, Krahn Katherine N, Gaur Naseem A, Ukomadu Chinweike

Abstract excerpt

In contrast to the deregulated hepatocellular division that is a feature of many hepatic diseases and malignancies, physiologic liver growth during embryonic development and after partial hepatectomy (PH) in adults is characterized by tightly controlled cell proliferation. We used forward genetic screening in zebrafish to test the hypothesis that a similar genetic program governs physiologic liver growth during...

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Identifiers

PMID: 17242348
DOI: 10.1073/pnas.0610774104
PMCID: PMC1785278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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