Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis

14 Feb 2013

Abstract excerpt

Dysfunction or death of photoreceptors is the primary cause of vision loss in retinal and macular degenerative diseases. As photoreceptors have an intimate relationship with the retinal pigment epithelium (RPE) for exchange of macromolecules, removal of shed membrane discs and retinoid recycling, an improved understanding of the development of the photoreceptor-RPE complex will allow better design of gene- and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Photoreceptor and optogenetics research
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23406904
DOI: 10.1242/dev.086603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesisPMID 23406904Read ↗

Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina.Semantic proximity Read ↗

DNA methylation and differential gene regulation in photoreceptor cell death.Semantic proximity Read ↗

Transient DNA methyltransferase 3a (DNMT3a) Inhibition Unlocks dedifferentiation and Neurogenic Potential in Mouse Retinal Müller GliaSemantic proximity Read ↗

The retinal pigmented epithelium – from basic developmental biology research to translational approachesSemantic proximity Read ↗

DNA demethylation is a driver for chick retina regenerationSemantic proximity Read ↗

Dysregulated DNA Methylation in Retinal Pigment Epithelium During the Early Stage of Stargardt DiseaseSemantic proximity Read ↗

The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachmentSemantic proximity Read ↗

DICER1 is essential for survival of postmitotic rod photoreceptor cells in miceSemantic proximity Read ↗

Pigment epithelial and retinal phenotypes in the vitiligo mivit, mutant mouse.Semantic proximity Read ↗

Advances in Ophthalmic Epigenetics and Implications for Epigenetic Therapies: A ReviewSemantic proximity Read ↗

DNA methylation plays important roles in retinal development and diseasesSemantic proximity Read ↗

The Potential Role of Epigenetic Mechanisms in the Development of Retinitis Pigmentosa and Related Photoreceptor DystrophiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.