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Prox1 function is crucial for mouse lens-fibre elongation.

Nature genetics - 1 Mar 1999

Wigle J T, Chowdhury K, Gruss P, Oliver G

Abstract excerpt

Although insights have emerged regarding genes controlling the early stages of eye formation, little is known about lens-fibre differentiation and elongation. The expression pattern of the Prox1 homeobox gene suggests it has a role in a variety of embryonic tissues, including lens. To analyse the...

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beta-Galactosidase
Bromodeoxyuridine
Crystallins
Cyclin-Dependent Kinase Inhibitor p27
Embryonic Induction
Lens, Crystalline

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Microtubule-Associated Proteins

Molecular Motor Proteins

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PMID: 10080188
DOI: 10.1038/6844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10080188-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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