Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration.

Journal of neuroinflammation - 2 Dec 2010

Raoul William, Auvynet Constance, Camelo Serge, Guillonneau Xavier, Feumi Charles, Combadière Christophe, Sennlaub Florian

Abstract excerpt

The causes of age-related macular degeneration (AMD) are not well understood. Due to demographic shifts in the industrialized world a growing number of people will develop AMD in the coming decades. To develop treatments it is essential to characterize the disease's pathogenic process. Over the past few years, numerous studies have focused on the role of chemotactic cytokines, also known as chemokines. Certain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokine CCL2
Share to CX3C Chemokine Receptor 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Macular Degeneration

Share to Mice, Knockout

Share to Receptors, CCR2

Share to Receptors, Chemokine

Share to Retina

Source

Open in PubMed Open full text

Identifiers

PMID: 21126357
DOI: 10.1186/1742-2094-7-87
PMCID: PMC3003653

Genes

CCL2
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration.PMID 21126357Read ↗

Investigating Chemokine-Induced NF-κB Activation in Retinal Cells and Its Contribution to Age-Related Macular Degeneration Pathogenesis: A Systematic ReviewSemantic proximity Read ↗

Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration.Semantic proximity Read ↗

Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling.Semantic proximity Read ↗

Single nucleotide polymorphisms in MCP-1 and its receptor are associated with the risk of age related macular degeneration.Semantic proximity Read ↗

CX3CR1 polymorphisms and the risk of age-related macular degeneration.Semantic proximity Read ↗

CCR1 Signaling as a Common Injury Pathway in Retinal DegenerationSemantic proximity Read ↗

CCL2 single nucleotide polymorphism of rs1024611 implicates prominence of inflammatory cascade by univariate modeling in Indian AMD.Semantic proximity Read ↗

Retinal Phenotype following Combined Deletion of the Chemokine Receptor CCR2 and the Chemokine CX3CL1 in Mice.Semantic proximity Read ↗

Molecular pathology of age-related macular degeneration.Semantic proximity Read ↗

Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration.Semantic proximity Read ↗

Overstaying their welcome: defective CX3CR1 microglia eyed in macular degeneration.Semantic proximity Read ↗

CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.