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Article

Single nucleotide polymorphisms in MCP-1 and its receptor are associated with the risk of age related macular degeneration.

PloS one - 1 Jan 2012

Anand Akshay, Sharma Neel Kamal, Gupta Amod, Prabhakar Sudesh, Sharma Suresh Kumar, Singh Ramandeep, Gupta Pawan Kumar

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. We have shown previously that mice deficient in monocyte chemoattractant protein-1 (MCP1/CCL2) or its receptor (CCR2) develop the features of AMD in senescent mice, however, the human g...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23185481
DOI: 10.1371/journal.pone.0049905
PMCID: PMC3503775

Genes

CCL2
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23185481-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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