Article

Investigating Chemokine-Induced NF-κB Activation in Retinal Cells and Its Contribution to Age-Related Macular Degeneration Pathogenesis: A Systematic Review

2024-09-08

Abstract excerpt

<h4>Objective</h4> To investigate the roles of chemokines in activating the NF-κB signaling pathway in retinal pigment epithelium (RPE) and photoreceptor cells, and their contribution to the pathogenesis of age-related macular degeneration (AMD). <h4>Background</h4> AMD is a leading cause of vision loss in older adults, driven by chronic inflammation and oxidative stress. The NF-κB transcription factor plays a key...

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Literature Corpus work: 42bdd704-2056-5df7-8c11-6b8b7d787562
DOI: 10.1101/2024.09.07.24313230

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