Article
Molecular pathology of age-related macular degeneration.
Progress in retinal and eye research - 1 Jan 2009
Ding Xiaoyan, Patel Mrinali, Chan Chi-Chao
Abstract excerpt
Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the world. Although the etiology and pathogenesis of AMD remain largely unclear, a complex interaction of genetic and environmental factors is thought to exist. AMD pathology is characterized by degeneration involving the retinal photoreceptors, retinal pigment epithelium, and Bruch's membrane, as well as, in some cases,...
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