CX3CR1 polymorphisms and the risk of age-related macular degeneration.

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Article

CX3CR1 polymorphisms and the risk of age-related macular degeneration.

International journal of clinical and experimental pathology - 1 Jan 2015

Ma Baofeng, Dang Guangfu, Yang Shaoyuan, Duan Lian, Zhang Yanwei

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD), a most common eye disease, can lead to irreversible visual impairment. Age, genetic and environmental factors have been implicated in AMD. Chemokine (C-X3-C motif) receptor 1 (CX3CR1) gene polymorphisms could influence the susceptibility of AMD. METHODS: We tested the association between AMD and single nocleotide polymorphisms (SNPs) of CX3CR1 gene (rs3732378...

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PMID: 26464724
PMCID: PMC4583956

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