CCL2 single nucleotide polymorphism of rs1024611 implicates prominence of inflammatory cascade by univariate modeling in Indian AMD.

doi:10.1371/journal.pone.0193423

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Article

CCL2 single nucleotide polymorphism of rs1024611 implicates prominence of inflammatory cascade by univariate modeling in Indian AMD.

PloS one - 1 Jan 2018

Sharma Neel Kamal, Sharma Kaushal, Singh Ramandeep, Sharma Suresh Kumar, Anand Akshay

Abstract excerpt

BACKGROUND: The role of chemotactic protein CCL2/MCP-1 has been widely explored in age related macular degeneration (AMD) patients as well as animal models through our previous studies. AIM: Aim of the study was to examine the association of another variance of CCL2, rs1024611 in pathophysiology of AMD. METHODS: This particular SNP has been found to be involved in inflammatory processes in various diseases. Total...

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PMID: 29664944
DOI: 10.1371/journal.pone.0193423
PMCID: PMC5903598

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CCL2

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