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Article

Mechanism of cohesin loading onto chromosomes: a conformational dynamics study.

Biophysical journal - 9 Aug 2010

Kurkcuoglu Ozge, Bates Paul A

Abstract excerpt

The structure-function relationship of cohesin, an essential chromosome maintenance protein, is investigated by analyzing its collective dynamics and conformational flexibility, enhancing our understanding of the sister chromatid cohesion process. A three-dimensional model of cohesin has been constructed by homology modeling using both crystallographic and electron microscopy image data. The harmonic dynamics of...

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Identifiers

PMID: 20713005
DOI: 10.1016/j.bpj.2010.06.006
PMCID: PMC2920725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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