Article

Solution conformational differences between conventional and CENP-A nucleosomes are accentuated by reversible deformation under high pressure

2025-01-21

Abstract excerpt

Solution-based interrogation of the physical nature of nucleosomes has its roots in X-ray and neutron scattering experiments, including those that provided the initial observation that DNA wraps around core histones. In this study, we performed a comprehensive small-angle scattering study to compare canonical nucleosomes with variant centromeric nucleosomes harboring the histone variant, CENP-A. We used nucleosome...

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Literature Corpus work: f45460cd-0dbf-5c17-a54d-a8cd3f41b6a9
DOI: 10.1101/2025.01.16.633457

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Solution conformational differences between conventional and CENP-A nucleosomes are accentuated by reversible deformation under high pressureDOI 10.1101/2025.01.16.633457Read

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