Article
Using deformation energy to analyze nucleosome positioning in genomes.
Genomics - 1 Mar 2016
Chen Wei, Feng Pengmian, Ding Hui, Lin Hao, Chou Kuo-Chen
Abstract excerpt
By modulating the accessibility of genomic regions to regulatory proteins, nucleosome positioning plays important roles in cellular processes. Although intensive efforts have been made, the rules for determining nucleosome positioning are far from satisfaction yet. In this study, we developed a biophysical model to predict nucleosomal sequences based on the deformation energy of DNA sequences, and validated it...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
