Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Site-to-site mutational dissection of fission yeast cohesin reveals its dynamics.

G3 (Bethesda, Md.) - 9 Jul 2025

Wei Qi, Wang Li, Zhang Yichen, Abulimiti Saidaiguli, Wang Jie, Xu Xingya

Abstract excerpt

Cohesin is a heteropentameric protein complex that holds sister chromatids together from S phase to anaphase. Its 2 structural maintenance of chromosome subunits form a heterodimer, consisting of an ATPase head domain and a hinge domain connected by long coiled coils. Kleisin subunit associates with the head. Here, using Schizosaccharomyces pombe, we genetically dissected cohesin dynamics based on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Cell Cycle Proteins
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohesins

Share to Mutagenesis, Site-Directed

Share to Protein Domains

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 40388360
DOI: 10.1093/g3journal/jkaf111
PMCID: PMC12239626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Site-to-site mutational dissection of fission yeast cohesin reveals its dynamics.PMID 40388360Read ↗

Cohesin organization, dynamics, and subdomain functions revealed by genetic suppressor screening.Semantic proximity Read ↗

Cohesin ATPase activities regulate DNA binding and coiled-coil configuration.Semantic proximity Read ↗

Suppressor mutation analysis combined with 3D modeling explains cohesin's capacity to hold and release DNA.Semantic proximity Read ↗

Cohesin Mutations in Cancer.Semantic proximity Read ↗

Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe.Semantic proximity Read ↗

More to cohesin than meets the eye: complex diversity for fine-tuning of function.Semantic proximity Read ↗

Pds5 regulates sister chromatid cohesion by controlling cohesin ATPase activity through the Eco1-Smc3 acetylation pathway.Semantic proximity Read ↗

Fdo1, Fkh1, Fkh2 and the Swi6-Mbp1 MBF complex regulate Mcd1 levels to impact eco1 rad61 cell growth in Saccharomyces cerevisiaeSemantic proximity Read ↗

Emerging themes in cohesin cancer biology.Semantic proximity Read ↗

A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.Semantic proximity Read ↗

Genome stability: What we have learned from cohesinopathies.Semantic proximity Read ↗

Specialized interfaces of Smc5/6 control hinge stability and DNA association.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.