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Article

Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs.

BMC genetics - 14 Jul 2010

Chiu Yen-Feng, Chiou Jeng-Min, Liang Kung-Yee, Lee Chun-Yi

Abstract excerpt

BACKGROUND: Many dichotomous traits for complex diseases are often involved more than one locus and/or associated with quantitative biomarkers or environmental factors. Incorporating these quantitative variables into linkage analysis as well as localizing two linked disease loci simultaneously could therefore improve the efficiency in mapping genes. We extended the robust multipoint Identity-by-Descent (IBD)...

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Identifiers

PMID: 20626914
DOI: 10.1186/1471-2156-11-67
PMCID: PMC3247820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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