Article
Robust multipoint identical-by-descent mapping for affected relative pairs.
American journal of human genetics - 1 Jan 2005
Schaid Daniel J, Sinnwell Jason P, Thibodeau Stephen N
Abstract excerpt
The genetic mapping of complex traits has been challenging and has required new statistical methods that are robust to misspecified models. Liang et al. proposed a robust multipoint method that can be used to simultaneously estimate, on the basis of sib-pair linkage data, both the position of a t...
Topics
- Chromosome Mapping
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Male
- Models, Genetic
- Models, Statistical
- Pedigree
- Prostatic Neoplasms
- Quantitative Trait, Heritable