Article
Novel strategies to identify relevant molecular signatures for complex human diseases based on data of identical-by-decent profiles and genomic context.
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Feb 2006
Li Chuan-xing, Du Lei, Li Xia, Gong Bin-sheng, Zhang Jie, Rao Shao-qi
Abstract excerpt
OBJECTIVE: To develop novel strategies to identify relevant molecular signatures for complex human diseases based on data of identical-by-decent profiles and genomic context. METHODS: In the proposed strategies, we define four relevancy criteria for mapping SNP-phenotype relationships-point-wise IBD mean difference, averaged IBD difference for window, Z curve and averaged slope for window. RESULTS: Application of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
