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Article

Robust multipoint simultaneous identical-by-descent mapping for two linked loci.

Human heredity - 1 Jan 2007

Lin Wan-Yu, Schaid Daniel J

Abstract excerpt

A challenging issue in genetic mapping of complex human diseases is localizing disease susceptibility genes when the genetic effects are small to moderate. There are greater complexities when multiple loci are linked to a chromosomal region. Liang et al. [Hum Hered 2001;51:64-78] proposed a robust multipoint method that can simultaneously estimate both the position of a trait locus and its effect on disease...

Topics

Bias
Chromosome Mapping
Chromosomes, Human, Pair 20
Female
Genetic Markers
Genetic Predisposition to Disease
Humans
Male
Models, Genetic
Pedigree
Prostatic Neoplasms
Siblings

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17215580
DOI: 10.1159/000098460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17215580-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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