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Article

Affected relative pairs and simultaneous search for two-locus linkage in the presence of epistasis.

Genetic epidemiology - 1 Jul 2007

Schaid Daniel J, McDonnell Shannon K, Carlson Erin E, Thibodeau Stephen N, Ostrander Elaine A, Stanford Janet L

Abstract excerpt

It is commonly believed that multiple interacting genes increase the susceptibility of genetically complex diseases, yet few linkage analyses of human diseases scan for more than one locus at a time. To overcome some of the statistical and computational limitations of a simultaneous search for two disease susceptibility loci in the presence of epistasis, we developed new score statistics to simultaneously scan...

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PMID: 17410530
DOI: 10.1002/gepi.20223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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