Article
Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco).
International journal of dermatology - 1 Jun 2010
Segat Ludovica, Guimarães Rafael L, Brandão Lucas A C, Rocha Cintia R C, Zanin Valentina, Trevisiol Chiara, de Lima Filho José Luiz, Crovella Sergio
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin disease resulting from the interplay between environmental, immunological and genetic factors. In our study, we investigated the role of three single nucleotide polymorphisms (SNPs) at 5'-UTR of DEFB1 gene, encoding for the human beta defensin-1, on the susceptibility to develop AD in a group of Brazilian children and adolescents. METHODS: Three...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.