Article
Association of beta-defensin 1 single nucleotide polymorphisms with atopic dermatitis.
International archives of allergy and immunology - 1 Jan 2007
Prado-Montes de Oca Ernesto, García-Vargas Alejandro, Lozano-Inocencio Reymundo, Gallegos-Arreola Martha Patricia, Sandoval-Ramírez Lucila, Dávalos-Rodríguez Nory Omara, Figuera Luis Eduardo
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a chronic multifactorial allergic disease with unclear etiology. The antimicrobial human beta-defensin 1 is chemotactic for dendritic cells, which are important regulators of allergic immune responses. In an attempt to identify useful markers that could predict susceptibility to AD, we investigated single nucleotide polymorphisms (SNPs) of the beta-defensin 1 gene (DEFB1)...
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