Article
Single nucleotide polymorphisms and the haplotype in the DEFB1 gene are associated with atopic dermatitis in a Korean population.
Journal of dermatological science - 1 Apr 2009
Kim Eugene, Lee Jong-Eun, Namkung Jung-Hyun, Kim Pyoung-Su, Kim Sook, Shin Eun-Soon, Cho Eun-Young, Yang Jun-Mo
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) patients have been recognized to have an increased susceptibility to cutaneous colonization and infection by bacteria, fungi and viruses. OBJECTIVE: We wanted to evaluate the associations of single nucleotide polymorphism (SNP) and the haplotype in the defensin (DEFA) and defensin (DEFB) genes, and so we performed genotyping for the SNPs in these genes in both AD patients and...
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