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Article

Asthma and atopy are associated with DEFB1 polymorphisms in Chinese children.

Genes and immunity - 1 Jan 2006

Leung T F, Li C Y, Liu E K H, Tang N L S, Chan I H S, Yung E, Wong G W K, Lam C W K

Abstract excerpt

Human beta-defensin (HBD)-1 is constitutively expressed in the airway, and hBD-1 plays crucial roles in innate immunity against respiratory pathogens. Asthma was associated with DEFB1 polymorphisms in Caucasians. This study investigates whether three single nucleotide polymorphisms (SNPs) in 5'-untranslated region of DEFB1 are associated with asthma phenotypes in Chinese children. Subjects aged 5-18 years were...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16435024
DOI: 10.1038/sj.gene.6364279

Genes

DEFB1
GCA
HBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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