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Article

DEFB1 polymorphisms and salivary hBD-1 concentration in Oral Lichen Planus patients and healthy subjects.

Archives of oral biology - 1 Jan 2017

Polesello Vania, Zupin Luisa, Di Lenarda Roberto, Biasotto Matteo, Pozzato Gabriele, Ottaviani Giulia, Gobbo Margherita, Crovella Sergio, Segat Ludovica

Abstract excerpt

OBJECTIVES: The aetiology of Oral Lichen Planus (OLP), a chronic inflammatory disease of oral mucosa, is not yet well understood. Since innate immunity may be hypothesized as involved in the susceptibility to OLP, we studied human beta defensin 1 (hBD-1) an antimicrobial peptide constitutively expressed in the saliva, looking at functional genetic variants possibly able to diminish hBD-1 production an...

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5' Untranslated Regions
Aged
Aged, 80 and over
beta-Defensins
Lichen Planus, Oral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Sequence Analysis, DNA

Source

Identifiers

PMID: 27770642
DOI: 10.1016/j.archoralbio.2016.10.008

Genes

DEFB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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