Article
Evaluation of DEFB1 polymorphisms in individuals with chronic periodontitis and diabetes mellitus type 2 in a population of northeastern Brazil.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry - 1 Jul 2018
Soraia Aguiar de Melo Dias Rayanne, Carlos Mourão Pinho Roberto, Almeida Felipe Rodrigues de, Alfredo Farias Bandeira Francisco, Celerino da Silva Ronaldo, Crovella Sergio, de Carvalho Farias Vajgel Bruna, Cimões Renata
Abstract excerpt
AIMS: The role of genetic variations in genes related to innate response, as β-defensin-1 (DEFB1), in the context of chronic periodontitis (CP) and diabetes mellitus type 2 (DM2), is still not clear. The present study evaluates the distribution of DEFB1 single nucleotide polymorphisms (SNPs) 5'-untranslated (5'UTR) region and its relation with the CP in DM2 individuals in northeastern Brazilians. METHODS: Two...
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