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Article

DEFB1 polymorphisms are involved in susceptibility to human papillomavirus infection in Brazilian gynaecological patients.

Memorias do Instituto Oswaldo Cruz - 1 Nov 2014

Segat Ludovica, Zupin Luisa, Moura Ronald Rodrigues, Coelho Antonio Victor Campos, Chagas Bárbara Simas, de Freitas Antonio Carlos, Crovella Sergio

Abstract excerpt

The human beta defensin 1 (hBD-1) antimicrobial peptide is a member of the innate immune system known to act in the first line of defence against microorganisms, including viruses such as human papillomavirus (HPV). In this study, five functional polymorphisms (namely g-52G>A, g-44C>G and g-20G>A in the 5'UTR and c.*5G>A and c.*87A>G in the 3'UTR) in the DEFB1 gene encoding for hBD-1 were analysed to investigate...

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Identifiers

PMID: 25410996
DOI: 10.1590/0074-0276140220
PMCID: PMC4296497

Genes

DEFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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