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Article

Caries and Innate Immunity: DEFB1 Gene Polymorphisms and Caries Susceptibility in Genetic Isolates from North-Eastern Italy.

Caries research - 1 Jan 2016

Navarra Chiara O, Robino Antonietta, Pirastu Nicola, Bevilacqua Lorenzo, Gasparini Paolo, Di Lenarda Roberto, Crovella Sergio

Abstract excerpt

BACKGROUND: The DEFB1 gene, encoding for the constitutively expressed human β-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. METHODS: We analysed 5 DEFB1...

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Identifiers

PMID: 27846636
DOI: 10.1159/000450965

Genes

DEFB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Caries and Innate Immunity: DEFB1 Gene Polymorphisms and Caries Susceptibility in Genetic Isolates from North-Eastern Italy.PMID 27846636Read ↗

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