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Article

The Ser(326)Cys polymorphism of 8-oxoguanine glycosylase 1 (OGG1) is associated with type 2 diabetes in Mexican Americans.

Human heredity - 1 Jan 2010

Thameem Farook, Puppala Sobha, Lehman Donna M, Stern Michael P, Blangero John, Abboud Hanna E, Duggirala Ravindranath, Habib Samy L

Abstract excerpt

OBJECTIVE: Human 8-oxoguanine glycosylase 1 (OGG1) excises oxidatively damaged promutagenic base 8-oxoguanine, a lesion previously observed in a rat model of type 2 diabetes (T2DM). The objective of the present study is to determine whether genetic variation in OGG1 is associated with type 2 diabetes (T2DM) in a Mexican American cohort. METHODS: Ten SNPs including two tagging SNPs (rs1052133, rs2072668) across...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2
Share to DNA Glycosylases
Share to Genetic Association Studies
Share to Genetic Predisposition to Disease
Share to Linkage Disequilibrium
Share to Mexican Americans
Share to Polymorphism, Single Nucleotide
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Source

Open in PubMed Open full text

Identifiers

PMID: 20606456
DOI: 10.1159/000291964
PMCID: PMC3083264

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Ser(326)Cys polymorphism of 8-oxoguanine glycosylase 1 (OGG1) is associated with type 2 diabetes in Mexican Americans.PMID 20606456Read ↗

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