Article
Association of the Ser326Cys polymorphism in the OGG1 gene with type 2 DM.
Biochemical and biophysical research communications - 14 Aug 2009
Daimon Makoto, Oizumi Toshihide, Toriyama Sayumi, Karasawa Shigeru, Jimbu Yumi, Wada Kiriko, Kameda Wataru, Susa Shinji, Muramatsu Masaaki, Kubota Isao, Kawata Sumio, Kato Takeo
Abstract excerpt
The association of the Ser326Cys polymorphism of the 8-oxoguanine glycosylase 1 (OGG1) gene with type 2 diabetes was examined using a Japanese population (n (M/W): 4585 (2085/2500); age: 62.6 +/- 10.9 years). HbA1c levels and frequency of diabetic subjects were significantly higher in subjects with genotypes with Cys allele than in those without (p = 0.032 and 0.037, respectively). Multiple logistic regression...
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