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Article

Impact of the Ser326Cys polymorphism of the OGG1 gene on the level of oxidative DNA damage in patients with colorectal cancer.

Polski przeglad chirurgiczny - 30 Apr 2018

Kabzinski Jacek, Walczak Anna, Dziki Adam, Mik Michał, Majsterek Ireneusz

Abstract excerpt

As a result of reactive oxygen species operation, cell damage occurs in both cellular organelles and molecules, including DNA. Oxidative damage within the genetic material can lead to accumulation of mutations and consequently to cancer transformation. OGG1 glycosylase, a component of the Base Excision Repair (BER) system, is one of the enzymes that prevents excessive accumulation of 8-oxoguanine (8-oxG), the...

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Source

Identifiers

PMID: 29773766
DOI: 10.5604/01.3001.0011.7486

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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