Article
Parameters of oxidative stress, DNA damage and DNA repair in type 1 and type 2 diabetes mellitus.
Archives of physiology and biochemistry - 1 Oct 2011
Pácal Lukáš, Varvařovská Jana, Rušavý Zdeněk, Lacigová Silva, Stětina Rudolf, Racek Jaroslav, Pomahačová Renata, Tanhäuserová Veronika, Kaňková Kateřina
Abstract excerpt
OBJECTIVES: (i) to determine the extent of oxidative stress and DNA damage and repair using a panel of selected markers in patients with type 1 and type 2 diabetes mellitus (T1DM, T2DM), (ii) to find their possible relationships with diabetes compensation and duration, and finally (iii) to test for the effect of functional polymorphisms in the 8-oxoguanin DNA glycosylase (rs1052133), catalase (rs1001179) and...
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