Article
mbmdr: an R package for exploring gene-gene interactions associated with binary or quantitative traits.
Bioinformatics (Oxford, England) - 1 Sept 2010
Calle M Luz, Urrea Víctor, Malats Núria, Van Steen Kristel
Abstract excerpt
SUMMARY: We describe mbmdr, an R package for implementing the model-based multifactor dimensionality reduction (MB-MDR) method. MB-MDR has been proposed by Calle et al. as a dimension reduction method for exploring gene-gene interactions in case-control association studies. It is an extension of the popular multifactor dimensionality reduction (MDR) method of Ritchie et al. allowing a more flexible definition of...
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