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Article

A unified model based multifactor dimensionality reduction framework for detecting gene-gene interactions.

Bioinformatics (Oxford, England) - 1 Sept 2016

Yu Wenbao, Lee Seungyeoun, Park Taesung

Abstract excerpt

MOTIVATION: Gene-gene interaction (GGI) is one of the most popular approaches for finding and explaining the missing heritability of common complex traits in genome-wide association studies. The multifactor dimensionality reduction (MDR) method has been widely studied for detecting GGI effects. However, there are several disadvantages of the existing MDR-based approaches, such as the lack of an efficient way of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27587680
DOI: 10.1093/bioinformatics/btw424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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