Article
[Detecting gene-gene/environment interactions by model-based multifactor dimensionality reduction].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Nov 2015
Fan Wei, Shen Chao, Guo Zhirong
Abstract excerpt
This paper introduces a method called model-based multifactor dimensionality reduction (MB-MDR), which was firstly proposed by Calle et al., and can be applied for detecting gene-gene or gene-environment interactions in genetic studies. The basic principle and characteristics of MB-MDR as well as the operation in R program are briefly summarized. Besides, the detailed procedure of MB-MDR is illustrated by using...
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