Article
Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions.
Bioinformatics (Oxford, England) - 1 Oct 2007
Lee Seung Yeoun, Chung Yujin, Elston Robert C, Kim Youngchul, Park Taesung
Abstract excerpt
MOTIVATION: The identification and characterization of susceptibility genes that influence the risk of common and complex diseases remains a statistical and computational challenge in genetic association studies. This is partly because the effect of any single genetic variant for a common and complex disease may be dependent on other genetic variants (gene-gene interaction) and environmental factors...
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