Article
UGMDR: a unified conceptual framework for detection of multifactor interactions underlying complex traits.
Heredity - 1 Mar 2015
Lou X-Y
Abstract excerpt
Biological outcomes are governed by multiple genetic and environmental factors that act in concert. Determining multifactor interactions is the primary topic of interest in recent genetics studies but presents enormous statistical and mathematical challenges. The computationally efficient multifactor dimensionality reduction (MDR) approach has emerged as a promising tool for meeting these challenges. On the other...
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