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Article

Multivariate Quantitative Multifactor Dimensionality Reduction for Detecting Gene-Gene Interactions.

Human heredity - 1 Jan 2015

Yu Wenbao, Kwon Min-Seok, Park Taesung

Abstract excerpt

OBJECTIVES: To determine gene-gene interactions and missing heritability of complex diseases is a challenging topic in genome-wide association studies. The multifactor dimensionality reduction (MDR) method is one of the most commonly used methods for identifying gene-gene interactions with dichotomous phenotypes. For quantitative phenotypes, the generalized MDR or quantitative MDR (QMDR) methods have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26201702
DOI: 10.1159/000377723

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