Article
Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions.
Bioinformatics (Oxford, England) - 1 Jan 2007
Chung Yujin, Lee Seung Yeoun, Elston Robert C, Park Taesung
Abstract excerpt
MOTIVATION: The identification and characterization of genes that increase the susceptibility to common complex multifactorial diseases is a challenging task in genetic association studies. The multifactor dimensionality reduction (MDR) method has been proposed and implemented by Ritchie et al. (2001) to identify the combinations of multilocus genotypes and discrete environmental factors that are associated with...
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