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Article

An empirical fuzzy multifactor dimensionality reduction method for detecting gene-gene interactions.

BMC genomics - 14 Mar 2017

Leem Sangseob, Park Taesung

Abstract excerpt

BACKGROUND: Detection of gene-gene interaction (GGI) is a key challenge towards solving the problem of missing heritability in genetics. The multifactor dimensionality reduction (MDR) method has been widely studied for detecting GGIs. MDR reduces the dimensionality of multi-factor by means of binary classification into high-risk (H) or low-risk (L) groups. Unfortunately, this simple binary classification does not...

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Identifiers

PMID: 28361694
DOI: 10.1186/s12864-017-3496-x
PMCID: PMC5374597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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