Article
Analysis of N-ras gene mutations in medulloblastomas by polymerase chain reaction and oligonucleotide probes in formalin-fixed, paraffin-embedded tissues.
Medical and pediatric oncology - 1 Jan 1991
Iolascon A, Lania A, Badiali M, Pession A, Saglio G, Giangaspero F, Miraglia del Giudice E, Perrotta S, Cutillo S
Abstract excerpt
Precise data on the incidence of transforming ras oncogenes in pediatric tumors and the correlations with the histopathological properties of the tumors are very limited. Additionally the presence of ras activation in medulloblastomas has not been investigated so far. Using a combination of techn...
Topics
- Adolescent
- Adult
- Base Sequence
- Blotting, Southern
- Cerebellar Neoplasms
- Child
- Child, Preschool
- DNA, Neoplasm
- Female
- Gene Amplification
- Genes, ras
- Humans
- Infant
- Male
- Medulloblastoma