Article
The ras oncogenes in human lung cancer.
The American review of respiratory disease - 1 Dec 1990
Rodenhuis S, Slebos R J
Abstract excerpt
The three well-characterized genes of the ras gene family H-ras, K-ras, and N-ras, code for closely related 21-kD proteins that have a role in the transduction of growth signals. The ras proteins acquire transforming potential when a point mutation in the gene leads to replacement of an amino aci...
Topics
- Adenocarcinoma
- Genes, ras
- Humans
- Lung Neoplasms
- Mutation
- Signal Transduction
- Transfection