Mutational activation of ras genes is absent in pediatric osteosarcoma.

doi:10.1016/0165-4608(94)00115-r

Back to search

Article

Mutational activation of ras genes is absent in pediatric osteosarcoma.

Cancer genetics and cytogenetics - 1 Jan 1995

Antillón-Klüssmann F, García-Delgado M, Villa-Elízaga I, Sierrasesúmaga L

Abstract excerpt

Activation of ras oncogenes is found in human cancers; overall it is observed in 15% of all neoplasms. The purpose of this study was to assess the extent of involvement of ras oncogenes in osteosarcoma. Tumor samples from a series of 49 pediatric patients diagnosed with osteosarcoma and treated a...

Topics

Base Sequence
Bone Neoplasms
Child
DNA, Neoplasm
Genes, ras
Humans
Molecular Sequence Data
Mutation
Osteosarcoma
Polymerase Chain Reaction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.