Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of RUNX3 in Bone Morphogenetic Protein Signaling in Colorectal Cancer

4 May 2010

Abstract excerpt

Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGF-beta) superfamily, are multifunctional cytokines regulating a broad spectrum of biological functions. Recent studies show the presence of BMP receptor 1a mutations in juvenile polyposis and frequent Smad4 mutations in colon cancer, suggesting that aberrations in BMP signaling play an important role in intestinal cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Genetic factors in colorectal cancer
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20442291
DOI: 10.1158/0008-5472.can-09-3805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of RUNX3 in Bone Morphogenetic Protein Signaling in Colorectal CancerPMID 20442291Read ↗

Molecular pathology of RUNX3 in human carcinogenesis.Semantic proximity Read ↗

Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer developmentSemantic proximity Read ↗

RUNX3 in oncogenic and anti‐oncogenic signaling in gastrointestinal cancersSemantic proximity Read ↗

Bone morphogenetic protein signaling and growth suppression in colon cancerSemantic proximity Read ↗

Epigenetic inactivation of <i>RUNX3</i> in microsatellite unstable sporadic colon cancersSemantic proximity Read ↗

The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcomeSemantic proximity Read ↗

RUNX3 suppresses metastasis and stemness by inhibiting Hedgehog signaling in colorectal cancerSemantic proximity Read ↗

Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior.Semantic proximity Read ↗

Oncogenic role of RUNX3 in head and neck cancerSemantic proximity Read ↗

Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cellsSemantic proximity Read ↗

Vitamin D Is a Multilevel Repressor of Wnt/b-Catenin Signaling in Cancer CellsSemantic proximity Read ↗

TGFbeta/BMP inhibits the bone marrow transformation capability of Hoxa9 by repressing its DNA-binding ability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.