Article
Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior.
Cancer genetics - 1 Jun 2012
Kallioniemi Anne
Abstract excerpt
Bone morphogenetic proteins (BMPs) are extracellular signaling molecules that belong to the transforming growth factor β (TGFβ) superfamily and are well-known for their indispensable roles in vertebrate development. In recent years, important new information has been generated on the contribution of BMP family members, such as BMP4, in cancer pathogenesis. First of all, BMP4 gene variants have been shown to...
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