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Article

Oncogenic role of RUNX3 in head and neck cancer

6 Dec 2010

Abstract excerpt

Cumulative evidences show that Runt-related transcription factor 3 (RUNX3) has a tumor suppressive role in various cancers. In particular, RUNX3 appears to be an important component of the transforming growth factor-β (TGF-β)-induced tumor suppression pathway. Contrary to reports on this tumor suppressive role of RUNX3, RUNX3 can also function as an oncogene when overexpressed. Recently, we found that RUNX3...

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Identifiers

PMID: 21268058
DOI: 10.1002/jcb.22967

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