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Article

Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells

3 Jul 2014

Abstract excerpt

Colorectal cancer (CRC) is one of the most deadly cancers worldwide. Significant progress has been made in understanding the molecular pathogenesis of CRC, which has led to successful early diagnosis, surgical intervention and combination chemotherapy. However, limited therapeutic options are available for metastatic and/or drug-resistant CRC. While the aberrantly activated Wnt/β-catenin pathway plays a critical...

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PMID: 24993644
DOI: 10.3892/or.2014.3308

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